dbEmbryo

dbEmbryo is an integrated multi-omics database designed to facilitate the analysis of early mammalian embryo development. It combines data from various epigenetic marks such as gene expression, DNA methylation, histone modifications, chromatin accessibility, and chromatin structure profiles, with a focus on human and mouse early embryos. The database includes customized analysis tools like multi-omics visualization, gene and peak annotation, ZGA gene cluster identification, and dynamic clustering to enable researchers to explore the interconnected functions of epigenetic markers and gene expression during early embryonic development.

Topic

Epigenetics;Transcription factors and regulatory sites;Gene regulation;ChIP-seq;Chromosome conformation capture

Detail

  • Operation: Gene expression profiling;Expression profile clustering;Data retrieval

  • Software interface: Database,Web user iinterface

  • Language: -

  • License: Not stated

  • Cost: Free

  • Version name: -

  • Credit: The National Natural Science Foundation of China, the Beijing Nova Program of Science and Technology.

  • Input: -

  • Output: -

  • Contact: Hebing Chen chenhb@bmi.ac.cn

  • Collection: -

  • Maturity: -

Publications

  • dbEmbryo multi-omics database for analyses of synergistic regulation in early mammalian embryo development.
  • Huang X, et al. dbEmbryo multi-omics database for analyses of synergistic regulation in early mammalian embryo development. dbEmbryo multi-omics database for analyses of synergistic regulation in early mammalian embryo development. 2022; 32:1612-25. doi: 10.1101/gr.276744.122
  • https://doi.org/10.1101/GR.276744.122
  • PMID: 35977841
  • PMC: PMC9435744

Download and documentation

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