easyRNASeq

"easyRNASeq" is an R package that simplifies the processing of RNA sequencing (RNA-Seq) data. With the advent of RNA-Seq as a standard for expression profiling experiments, the need for robust and user-friendly tools to analyze such data has become increasingly important. Although numerous Bioconductor packages exist for loading next-generation sequencing data into R (e.g., ShortRead, Rsamtools) and for performing differential gene expression analyses (e.g., DESeq, edgeR), the processing tasks that bridge these steps involve a complex combination of multiple packages such as Biostrings and IRanges or even external solutions.

easyRNASeq addresses this challenge by providing a streamlined interface that encapsulates the complexity of these intermediary processing steps. The package facilitates tasks such as the reading and summarization of RNA-Seq data, allowing researchers to focus on the analysis rather than the preprocessing intricacies.

Topic

RNA-seq;Sequence analysis

Detail

  • Operation: Gene expression profiling

  • Software interface: Command-line user interface,Library

  • Language: R

  • License: Artistic License 2.0

  • Cost: Free

  • Version name: 2.38.0

  • Credit: European Molecular Biology Laboratory, an ERASysBio grant ModHeart, NIH.

  • Input: -

  • Output: -

  • Contact: Nicolas Delhomme nicolas.delhomme@umu.se

  • Collection: -

  • Maturity: Stable

Publications

  • easyRNASeq: a bioconductor package for processing RNA-Seq data.
  • Delhomme N, et al. easyRNASeq: a bioconductor package for processing RNA-Seq data. easyRNASeq: a bioconductor package for processing RNA-Seq data. 2012; 28:2532-3. doi: 10.1093/bioinformatics/bts477
  • https://doi.org/10.1093/bioinformatics/bts477
  • PMID: 22847932
  • PMC: PMC3463124

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