enoLOGOS

enoLOGOS is a powerful and versatile web-based tool designed to generate sequence logos from various input sources easily and efficiently. Sequence logos have become a popular way to graphically represent DNA and amino acid sequence patterns from a set of aligned sequences, allowing researchers to visualize the conserved features of a given sequence.

One of the notable features of enoLOGOS is its ability to create logos directly from binding affinity data, which makes it highly valuable to researchers working with high-throughput technologies for estimating the contact energy of different DNA sequences. This feature eliminates the need for manual alignment, which can be time-consuming and error-prone, and ensures that the output is accurate and reliable.

enoLOGOS is designed to be highly flexible and can generate sequence logos from various input data, including energy measurements, probability matrices, alignment matrices, count matrices, and aligned sequences. This allows researchers to easily use their preferred data source and format with the tool, making it highly customizable and adaptable to different research needs.

In addition to these features, enoLOGOS stands out from other web servers by being able to represent the mutual information of different positions of the consensus sequence, a unique capability that provides valuable insights into the sequence patterns and their conservation. Another web interface for the software, C2H2-enoLOGOS, generates logos for the DNA-binding preferences of the C2H2 zinc-finger transcription factor family members, which is highly useful for researchers studying this specific transcription factor family.

Topic

Sequence analysis;Statistics and probability;Sequencing

Detail

  • Operation: Multiple sequence alignment;Sequence alignment analysis;Sequence alignment conversion;Sequence alignment

  • Software interface: Web user interface

  • Language: C++

  • License: -

  • Cost: Free

  • Version name: -

  • Credit: NSF, NCRR, NIH.

  • Input: -

  • Output: -

  • Contact: cworkman@bioeng.ucsd.edu

  • Collection: -

  • Maturity: -

Publications

  • enoLOGOS: a versatile web tool for energy normalized sequence logos.
  • Workman CT, et al. enoLOGOS: a versatile web tool for energy normalized sequence logos. enoLOGOS: a versatile web tool for energy normalized sequence logos. 2005; 33:W389-92. doi: 10.1093/nar/gki439
  • https://doi.org/10.1093/nar/gki439
  • PMID: 15980495
  • PMC: PMC1160200

Download and documentation

    Currently not available or not maintained.


< Back to DB search