gsrc

gsrc is a tool specifically designed to detect genome structure rearrangements in allopolyploid species. These species are known to exhibit deletions, duplications, and homeologous non-reciprocal translocations (HNRT) between highly similar subgenomes. The occurrence of these rearrangements can have a significant impact on phenotypic traits. However, the detection of these rearrangements using high-density array genotyping data is a more cost-effective alternative to sequencing approaches, which can be limited by their cost-intensive nature.

gsrc can reliably detect genome structure rearrangements using high-density array genotyping data, providing researchers with a valuable tool to study the impact of these rearrangements on phenotypic traits. The package was applied to a publicly available Brassica napus dataset as an example, demonstrating the tool's effectiveness in detecting genome structure rearrangements.

Topic

Structural genomics;Biomarkers;Comparative genomics

Detail

  • Operation: Filtering;Gene expression analysis

  • Software interface: Command-line user interface;Library

  • Language: R

  • License: GNU General Public License v3

  • Cost: Free

  • Version name: 1.1.1

  • Credit: DFG, BMBF.

  • Input: -

  • Output: -

  • Contact: birgit.samans@uni-giessen.de

  • Collection: -

  • Maturity: -

Publications

  • gsrc: an R package for genome structure rearrangement calling.
  • Grandke F, et al. gsrc: an R package for genome structure rearrangement calling. gsrc: an R package for genome structure rearrangement calling. 2017; 33:545-546. doi: 10.1093/bioinformatics/btw648
  • https://doi.org/10.1093/bioinformatics/btw648
  • PMID: 27797758
  • PMC: -

Download and documentation


< Back to DB search