gsrc
gsrc is a tool specifically designed to detect genome structure rearrangements in allopolyploid species. These species are known to exhibit deletions, duplications, and homeologous non-reciprocal translocations (HNRT) between highly similar subgenomes. The occurrence of these rearrangements can have a significant impact on phenotypic traits. However, the detection of these rearrangements using high-density array genotyping data is a more cost-effective alternative to sequencing approaches, which can be limited by their cost-intensive nature.
gsrc can reliably detect genome structure rearrangements using high-density array genotyping data, providing researchers with a valuable tool to study the impact of these rearrangements on phenotypic traits. The package was applied to a publicly available Brassica napus dataset as an example, demonstrating the tool's effectiveness in detecting genome structure rearrangements.
Topic
Structural genomics;Biomarkers;Comparative genomics
Detail
Operation: Filtering;Gene expression analysis
Software interface: Command-line user interface;Library
Language: R
License: GNU General Public License v3
Cost: Free
Version name: 1.1.1
Credit: DFG, BMBF.
Input: -
Output: -
Contact: birgit.samans@uni-giessen.de
Collection: -
Maturity: -
Publications
- gsrc: an R package for genome structure rearrangement calling.
- Grandke F, et al. gsrc: an R package for genome structure rearrangement calling. gsrc: an R package for genome structure rearrangement calling. 2017; 33:545-546. doi: 10.1093/bioinformatics/btw648
- https://doi.org/10.1093/bioinformatics/btw648
- PMID: 27797758
- PMC: -
Download and documentation
Source: https://github.com/grafab/gsrc
Documentation: https://github.com/grafab/gsrc/tree/master/vignettes
Home page: https://github.com/grafab/gsrc
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