iscGPS

The software tool 'iscGPS' (Single Cell Global fate Potential of Subpopulations) designed to address a key challenge in developmental biology and single-cell data analysis: determining the relatedness of cells in a differentiation lineage. Traditional approaches to analyzing single-cell data focus on identifying cell states and their clustering but often lack a seamless pipeline for estimating the transition probabilities between these cell clusters. iscGPS aims to fill this gap by providing a comprehensive analysis tool that identifies cell clusters and estimates the likelihood of transitions between them, thereby offering insights into the developmental lineage and fate potential of different cell subpopulations.