massPix

massPix is an open-source R package designed for analyzing and interpreting complex multi-dimensional datasets generated from mass spectrometry imaging (MSI) experiments, particularly in lipidomics applications. The software offers a range of features to facilitate the processing and understanding of MSI data.

Key features of massPix include: 1. Generation of single ion images from the MSI data.

2. Multivariate statistical analyses, such as principal components analysis (PCA) and k-means clustering, are performed to classify tissue regions with high spectral similarity.

3. Providing putative lipid annotations by accurately matching the mass of detected compounds against generated lipid libraries.

Topic

Proteomics experiment;Statistics and probability;Imaging;Metabolomics

Detail

  • Operation: Spectral analysis;Image analysis

  • Software interface: Library

  • Language: R

  • License: Not stated

  • Cost: Free of charge

  • Version name: -

  • Credit: The Medical Research Council (Lipid Profiling and Signalling & Lipid Dynamics and Regulation).

  • Input: -

  • Output: -

  • Contact: Julian L. Griffin jlg40@cam.ac.uk

  • Collection: -

  • Maturity: -

Publications

  • massPix: an R package for annotation and interpretation of mass spectrometry imaging data for lipidomics.
  • Bond NJ, et al. massPix: an R package for annotation and interpretation of mass spectrometry imaging data for lipidomics. massPix: an R package for annotation and interpretation of mass spectrometry imaging data for lipidomics. 2017; 13:128. doi: 10.1007/s11306-017-1252-5
  • https://doi.org/10.1007/s11306-017-1252-5
  • PMID: 28989334
  • PMC: PMC5608769

Download and documentation

< Back to DB search