miRMOD

miRMOD is a user-friendly software tool developed for the identification and analysis of miRNA modifications in sRNA NGS data. The tool is Windows-based and GUI-based, enabling users with little knowledge of computers to explore miRNA modifications. miRMOD identifies and analyzes 5' and 3' miRNA modifications (non-templated nucleotide additions and trimming) in sRNA NGS data, and also predicts and compares the targets of query and modified miRNAs. In addition, miRMOD utilizes minimum free energies of the miRNA:target and modified-miRNA:target interactions to compare binding affinities for the same target. The package is available as a stand-alone tool and is freely available for use.

Topic

Functional, regulatory and non-coding RNA;Sequencing;RNA

Detail

  • Operation: Sequence analysis

  • Software interface: Command-line user interface;Graphical user interface

  • Language: C#

  • License: Other

  • Cost: Free

  • Version name: 0.4

  • Credit: The Department of Biotechnology (DBT, India), Bioinformatics Infrastructure Facility (BIF) at ICGEB, DBT-BINC fellowship, a Council for Scientific and Industrial Research (CSIR), India fellowship.

  • Input: -

  • Output: -

  • Contact: dinesh@icgeb.res.in

  • Collection: -

  • Maturity: -

Publications

  • miRMOD: a tool for identification and analysis of 5' and 3' miRNA modifications in Next Generation Sequencing small RNA data.
  • Kaushik A, et al. miRMOD: a tool for identification and analysis of 5' and 3' miRNA modifications in Next Generation Sequencing small RNA data. miRMOD: a tool for identification and analysis of 5' and 3' miRNA modifications in Next Generation Sequencing small RNA data. 2015; 3:e1332. doi: 10.7717/peerj.1332
  • https://doi.org/10.7717/peerj.1332
  • PMID: 26623179
  • PMC: PMC4662591

Download and documentation

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