omiRas
omiRas is an innovative and user-friendly web server designed to assist researchers in studying non-coding RNAs (ncRNAs) derived from next-generation sequencing experiments of two conditions. The tool allows users to annotate, compare, and visualize interaction networks of ncRNAs, which are essential for characterizing differentially expressed ncRNAs between two conditions such as healthy and diseased individuals.
The ncRNAome is a complex system comprising various RNAs, such as transfer RNA, small nucleolar RNA, and microRNA (miRNA). omiRas allows researchers to submit raw sequencing data and view static annotation results, which include length distribution, mapping statistics, alignments, and quantification tables for each library. Moreover, it provides lists of differentially expressed ncRNAs between conditions, which can be useful for revealing insights into molecular mechanisms underlying condition-specific phenotypic traits.
With omiRas, users can also create interactive network visualizations of user-selected miRNAs and their target genes. This feature is based on the combination of several miRNA-mRNA interaction databases. It provides an excellent way to explore the relationships between miRNAs and their target genes in a more detailed manner.
Topic
Gene expression;RNA-Seq;Functional, regulatory and non-coding RNA
Detail
Operation: Gene expression analysis
Software interface: Web user interface
Language: R, Python
License: -
Cost: Free
Version name: -
Credit: Bundesministerium für Bildung und Forschung (BMBF)
Input: -
Output: -
Contact: rotter@genxpro.de
Collection: -
Maturity: -
Publications
- omiRas: a Web server for differential expression analysis of miRNAs derived from small RNA-Seq data.
- Müller S, et al. omiRas: a Web server for differential expression analysis of miRNAs derived from small RNA-Seq data. omiRas: a Web server for differential expression analysis of miRNAs derived from small RNA-Seq data. 2013; 29:2651-2. doi: 10.1093/bioinformatics/btt457
- https://doi.org/10.1093/bioinformatics/btt457
- PMID: 23946503
- PMC: -
Download and documentation
Currently not available or not maintained.
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