omicade4

omicade4 is a comprehensive R/Bioconductor package designed to address the challenges of integrating and analyzing multi-omics data by applying multiple co-inertia analysis (MCIA). MCIA is an exploratory data analysis method that uncovers co-relationships between multiple high-dimensional datasets by projecting them into a shared dimensional space. This approach harmonizes diverse sets of features and enhances biological interpretation and pathway analysis by extracting the most variant information from each dataset.

Topic

Omics;Microarray experiment;Cell biology;Medicine;Gene expression;Bioinformatics

Detail

  • Operation: Treemap visualisation;Clustering;Dendrogram visualisation

  • Software interface: Command-line user interface,Library

  • Language: -

  • License: GNU General Public License, version 2

  • Cost: Free

  • Version name: 1.42.0

  • Credit: The Dana-Farber Cancer Institute Women’s Cancers Program, the Claudia Adams Barr foundation and the National Cancer Institute at the National Institutes of Health, the National Cancer Institute and the National Human Genome Research Institute, the National Human Genome Research Institute (NHGRI).

  • Input: Gene expression data [cel] [affymetrix] [dat]

  • Output: Image [Image format], Plot [Image format]

  • Contact: Chen Meng mengchen18@gmail.com

  • Collection: -

  • Maturity: Stable

Publications

  • A multivariate approach to the integration of multi-omics datasets.
  • Meng C, et al. A multivariate approach to the integration of multi-omics datasets. A multivariate approach to the integration of multi-omics datasets. 2014; 15:162. doi: 10.1186/1471-2105-15-162
  • https://doi.org/10.1186/1471-2105-15-162
  • PMID: 24884486
  • PMC: PMC4053266

Download and documentation


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