pSBVB
pSBVB (polyploid Sequence Based Virtual Breeding) is a flexible and efficient forward simulation software tool designed to evaluate genomic selection strategies in polyploid species. It simulates complex phenotypes based on input data such as founder population genotypes, causal variants, heritabilities, and pedigree information. pSBVB can handle various ploidy levels and recombination rates between homeologous chromosomes, making it suitable for allo- and autopolyploid species.
The tool outputs phenotype and genotype data for all individuals in the pedigree and can generate genomic relationship matrices. pSBVB enables researchers to assess the effectiveness of genomic selection strategies under different scenarios, such as varying SNP density, genetic architecture, or population size, and to optimize experimental designs for association studies in polyploid species.
Topic
Agricultural science;Genotype and phenotype;DNA polymorphism
Detail
Operation: SNP detection;Haplotype mapping;Genotyping
Software interface: Command-line interface
Language: R,Python
License: Not stated
Cost: Free of charge
Version name: -
Credit: Centro de Excelencia Severo Ochoa, Ministry of Economy and Science (MINECO, Spain).
Input: -
Output: -
Contact: M Pérez-Enciso miguel.perez@uab.es ,Laura Zingaretti laura.zingaretti@cragenomica.es
Collection: -
Maturity: -
Publications
- pSBVB: A Versatile Simulation Tool To Evaluate Genomic Selection in Polyploid Species.
- Zingaretti ML, et al. pSBVB: A Versatile Simulation Tool To Evaluate Genomic Selection in Polyploid Species. pSBVB: A Versatile Simulation Tool To Evaluate Genomic Selection in Polyploid Species. 2019; 9:327-334. doi: 10.1534/g3.118.200942
- https://doi.org/10.1534/g3.118.200942
- PMID: 30573468
- PMC: PMC6385978
Download and documentation
Documentation: https://lauzingaretti.github.io/pSBVB/
Home page: https://github.com/lauzingaretti/pSBVB
Links: https://github.com/lauzingaretti/pSBVB/blob/master/README.md
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