paxtoolsr
The "paxtoolsR" package stands out among other tools by offering R users unique functionalities for accessing and analyzing pathway data formatted in BioPAX and available through the Pathway Commons web service. It supports complex pathway analyses, making tasks such as extracting, merging, and validating BioPAX pathway data a breeze. This integration allows users to retrieve and query data from Pathway Commons and combine these data with local BioPAX datasets for enriched analyses, a feature not commonly found in other tools.
Key features of paxtoolsR include providing access to novel pathway datasets and offering advanced querying capabilities directly within the R programming environment, enhancing the ability of researchers to conduct sophisticated analyses, including data visualization and gene set enrichment analysis, by leveraging the comprehensive pathway information available through Pathway Commons.
Topic
Cell biology;Molecular interactions, pathways and networks
Detail
Operation: Database search;Metabolic network modelling;Gene regulatory network analysis;Formatting;Pathway or network visualisation
Software interface: Command-line user interface,Library
Language: R
License: The GNU General Public License v3.0
Cost: Free
Version name: 1.36.0
Credit: US National Institutes of Health, Ruth L. Kirschstein National Research Service Award, National Institute of General Medical Sciences (NIGMS).
Input: Pathway or network [BioPAX]
Output: Pathway or network [sif] [SBGN-ML]
Contact: Augustin Luna lunaa@cbio.mskcc.org
Collection: -
Maturity: Stable
Publications
- PaxtoolsR: pathway analysis in R using Pathway Commons.
- Luna A, et al. PaxtoolsR: pathway analysis in R using Pathway Commons. PaxtoolsR: pathway analysis in R using Pathway Commons. 2016; 32:1262-4. doi: 10.1093/bioinformatics/btv733
- https://doi.org/10.1093/bioinformatics/btv733
- PMID: 26685306
- PMC: PMC4824129
Download and documentation
Source: https://bioconductor.org/packages/release/bioc/src/contrib/paxtoolsr_1.36.0.tar.gz
Documentation: https://bioconductor.org/packages/release/bioc/manuals/paxtoolsr/man/paxtoolsr.pdf
Home page: http://bioconductor.org/packages/release/bioc/html/paxtoolsr.html
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