sRNA

sRNA is a software tool to analyze small RNA (sRNA) plant sequencing data. It can identify and quantify different types of sRNAs, such as microRNAs (miRNAs) and small interfering RNAs (siRNAs), and determine their association with various RNA-induced silencing complexes (RISCs) based on their size and molecular weight. The tool helps researchers study the loading efficiencies of different miRNAs into RISCs and understand the factors that control this process, such as the availability of ARGONAUTE (AGO) proteins and information associated with miRNA precursors.

Topic

Functional, regulatory and non-coding RNA;Plant biology;Gene transcripts

Detail

  • Operation: Parsing;miRNA target prediction;miRNA expression analysis

  • Software interface: Command-line user interface

  • Language: Shell,R

  • License: Not stated

  • Cost: Free of charge

  • Version name: -

  • Credit: The National Research, Development and Innovation Office.

  • Input: -

  • Output: -

  • Contact: Zoltán Havelda havelda.zoltan@abc.naik.hu

  • Collection: -

  • Maturity: -

Publications

  • AGO-unbound cytosolic pool of mature miRNAs in plant cells reveals a novel regulatory step at AGO1 loading.
  • Dalmadi Á, et al. AGO-unbound cytosolic pool of mature miRNAs in plant cells reveals a novel regulatory step at AGO1 loading. AGO-unbound cytosolic pool of mature miRNAs in plant cells reveals a novel regulatory step at AGO1 loading. 2019; 47:9803-9817. doi: 10.1093/nar/gkz690
  • https://doi.org/10.1093/NAR/GKZ690
  • PMID: 31392979
  • PMC: PMC6765109

Download and documentation


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