BIANCA

BIANCA (Brain Intensity AbNormality Classification Algorithm), part of the FSL package, is a software tool to segment white matter hyperintensities using Magnetic resonance imaging (MRI) data. The BIANCA algorithm uses a supervised learning method based on the k-nearest neighbor k-nearest neighbors (k-NN) algorithm with options to weight spatial information and average local spatial intensity together with user-specified options for locations and training points.

Topic

Neurology;MRI

Detail

  • Operation: Image analysis

  • Software interface: Command-line user interface;Graphical user interface

  • Language: Python

  • License: GNU General Public License v2 + file license

  • Cost: Free for non-commercial use

  • Version name: v6.0

  • Credit: p133">Legend: FE&#x000a0;=&#x000a0;Fixed Equal, AE&#x000a0;=&#x000a0;All Equal, FU&#x000a0;= Fixed Unbalanced number of training points; NB&#x000a0;=&#x000a0;no border. Panel H legend: a&#x000a0;=&#x000a0;high WMH load training subjects, FU training points, no patch, no border location for non-WMH training points, mask applied, threshold 0.9; b&#x000a0;=&#x000a0;high WMH load training subjects, FU training points, 2D patch D&#x000a0;=&#x000a0;3, no border location for non-WMH training points, mask applied, threshold 0.9.</p></div></div></div><p></p></div><div id="s0145" class="tsec sec"><h2 class="head no_bottom_margin" id="s0145title">Funding</h2><p id=" p136" class="p p-first-last">The Oxford Vascular Study has been funded by Wellcome Trust, Wolfson Foundation, UK Stroke Association and the NIHR Oxford Biomedical Research Centre. PMR is in receipt of an NIHR Senior Investigator Award and a Wellcome Trust Senior Investigator Award. LL has been funded by the China Scholarship Council. LG, WK and UGS are supported by the NIHR Oxford Biomedical Research Centre.</p></div><div id="ac0005" class="tsec sec"><h2 class="head no_bottom_margin" id="ac0005title">Acknowledgements</h2><div class="sec"><p id="

  • Input: -

  • Output: -

  • Contact: Ludovica Griffanti ludovica.griffanti@ndcn.ox.ac.uk, atlas: Harvard-Oxford: steve@fmrib.ox.ac.uk, JHU: susumu@mri.jhu.edu, Juelich: S.Eickhoff@fz-juelich.de, Thalamus: behrens@fmrib.ox.ac.uk, Cerebellum: j.diedrichsen@bangor.ac.uk, Striatum: andri.tziortzi@gmail.com

  • Collection: FSL

  • Maturity: Mature

Publications

  • BIANCA (Brain Intensity AbNormality Classification Algorithm): A new tool for automated segmentation of white matter hyperintensities.
  • Griffanti L, Zamboni G, Khan A, Li L, Bonifacio G, Sundaresan V, Schulz UG, Kuker W, Battaglini M, Rothwell PM, Jenkinson M. BIANCA (Brain Intensity AbNormality Classification Algorithm): A new tool for automated segmentation of white matter hyperintensities. Neuroimage. 2016 Nov 1;141:191-205. doi: 10.1016/j.neuroimage.2016.07.018. Epub 2016 Jul 9. PMID: 27402600; PMCID: PMC5035138.
  • https://doi.org/10.1016/j.neuroimage.2016.07.018
  • PMID: 27402600
  • PMC: PMC5035138

Download and documentation


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