PPICompare

PPICompare is a software to detect rewiring among protein-protein interactomes in grouped samples. The PPICompare algorithm can deduce which alterations cause rewiring and produce a set of minimal alterations required to explain changes between groups. PPIXpress is required to construct the input to PPICompare.

Topic

Systems biology;Genomics;Protein interactions

Detail

  • Operation: Protein interaction analysis

  • Software interface: Graphical user interface

  • Language: Java

  • License: GNU General Public License v3

  • Cost: Free

  • Version name: 1.04

  • Credit: The European Union’s Seventh Framework Programme (FP7/2007-2013).

  • Input: -

  • Output: -

  • Contact: Volkhard Helms volkhard.helms@bioinformatik.uni-saarland.de, Thorsten Will thorsten.will@bioinformatik.uni-saarland.de

  • Collection: -

  • Maturity: -

Publications

  • Rewiring of the inferred protein interactome during blood development studied with the tool PPICompare.
  • Will T, Helms V. Rewiring of the inferred protein interactome during blood development studied with the tool PPICompare. BMC Syst Biol. 2017 Apr 4;11(1):44. doi: 10.1186/s12918-017-0400-x. PMID: 28376810; PMCID: PMC5379774.
  • https://doi.org/10.1186/s12918-017-0400-x
  • PMID: 28376810
  • PMC: PMC5379774

Download and documentation

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