fastSTRUCTURE

fastSTRUCTURE is a software tool to estimate population structure using sizeable single nucleotide polymorphism (SNP) data sets. The fastSTRUCTURE algorithm uses a variational Bayesian framework, hierarchical priors, and heuristic scores to identify the number of populations and weak population structures within data. The Authors claim the fastSTRUCTURE to be close to two orders of magnitude faster than Structure and as accurate as ADMIXTURE.

Topic

Population genetics

Detail

  • Operation: Genetic variation analysis

  • Software interface: Command-line user interface, graphical user interface

  • Language: Python;Cython;C

  • License: The MIT licence

  • Cost: Free

  • Version name: 1.0

  • Credit: National Institutes of Health (NIH), the Howard Hughes Medical Institute.

  • Input: plink bed, strcture format

  • Output: -

  • Contact: Anil Raj rajanil@stanford.edu

  • Collection: -

  • Maturity: Stable

Publications

  • fastSTRUCTURE: variational inference of population structure in large SNP data sets.
  • Raj A, Stephens M, Pritchard JK. fastSTRUCTURE: variational inference of population structure in large SNP data sets. Genetics. 2014 Jun;197(2):573-89. doi: 10.1534/genetics.114.164350. Epub 2014 Apr 2. PMID: 24700103; PMCID: PMC4063916.
  • https://doi.org/10.1534/genetics.114.164350
  • PMID: 24700103
  • PMC: PMC4063916

Download and documentation

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