Yale study finds 'hyperhotspots' that could predict skin cancer risk

New research by Yale University scientists reports the discovery of 'hyperhotspots' in the human genome, locations that are up to 170-times more sensitive to ultraviolet radiation (UV) from sunlight compared to the genome average. Read more at Eurekalert.org

Definitive demonstration by synthesis of genome annotation completeness [Genetics][To top]

While the possibilities of living systems are theoretically near-infinite, the reality of biology at any instant is bounded. Here, we demonstrate how the discovery of functional information encoded in natural DNA sequences can be formally completed. Using bac Read more at Pnas.org

SECURE SYNOPSIS: 14 NOVEMBER 2019[To top]

SECURE SYNOPSIS: 14 NOVEMBER 2019 NOTE: Please remember that following answers are NOT model answers. They are NOT synopsis too if we go by definition of the term. What we are providing is content that both meets demand of the question and at the same tim Read more at Insightsonindia.com

Pawsey to get new super supercomputing cluster[To top]

Two of the clusters at the Pawsey Supercomputing Centre will be replaced with one brand new system.
Read more at Zdnet.com

What do we know about the gut microbiota in Parkinson's disease?[To top]

Since the discovery that the gut microbiome may play a role in the development of Parkinson's disease (PD), this fresh scientific approach has produced varying results. Scientists compare results of current research and provide recommendations to increase the Read more at Sciencedaily.com

Mitochondrial somatic mutations and the lack of viral genomic variation in recurrent respiratory papillomatosis[To top]

Mitochondrial somatic mutations and the lack of viral genomic variation in recurrent respiratory papillomatosis
Read more at Nature.com

Small RNAs link immune system and brain cells[To top]

A collaborative study carried out by the Institute of Pharmacology and Clinical Pharmacy at Goethe University (Professor Jochen Klein) and the Institute of Neurosciences at the Hebrew University of Jerusalem (Professor Hermona Soreq) shows sex-specific biases Read more at Eurekalert.org

Analysis of short tandem repeat expansions and their methylation state with nanopore sequencing[To top]

Expansions of short tandem repeats linked to neuropsychiatric disorders are measured by single-molecule sequencing.
Read more at Nature.com

15,000 Spaniards may unknowingly have hypophosphatasia bone disease[To top]

In adults, hypophosphatasia causes recurrent fractures and chronic pain. In the child population this disease can be much more serious and can even cause premature death, neurological disorders, and respiratory problems. Read more at Eurekalert.org

On the emergence of structural complexity in RNA replicators [BIOINFORMATICS][To top]

The RNA world hypothesis relies on the ability of ribonucleic acids to spontaneously acquire complex structures capable of supporting essential biological functions. Multiple sophisticated evolutionary models have been proposed for their emergence, but they o Read more at Cshlp.org

Fastest HPC Parallel File System at Any Price-Point Hits the Market[To top]

SUNNYVALE, Calif.--(BUSINESS WIRE)--Panasas announced that its re-engineered PanFS parallel file system on the Panasas ActiveStor Ultra appliance is now shipping and in early deployment Read more at Businesswire.com

ADVA and PSNC showcase 1200G channel transmission at SC19[To top]

DENVER--(BUSINESS WIRE)-- #100G--ADVA (FSE: ADV) today announced that its hosting a joint showcase with PSNC at SC19 that features the industrys first 1200Gbit/s optical channel transmission. Built upon the ADVA FSP 3000 TeraFlex terminal, the demo undersc Read more at Businesswire.com

QIAGEN Receives Several Conditional, Non-binding Indications of Interest, Enters Into Discussions to Explore Potential Strategic Alternatives[To top]

VENLO, Netherlands--(BUSINESS WIRE)---- $QGEN--QIAGEN receives several conditional, non-binding indications of interest, enters into discussions to explore potential strategic alternatives Read more at Businesswire.com

Genetic robustness of let-7 miRNA sequence-structure pairs [BIOINFORMATICS][To top]

Genetic robustness, the preservation of evolved phenotypes against genotypic mutations, is one of the central concepts in evolution. In recent years a large body of work has focused on the origins, mechanisms, and consequences of robustness in a wide range of Read more at Cshlp.org

How Big Data Is Changing Science[To top]

New biomedical techniques, like next-generation genome sequencing, are creating vast amounts of data and transforming the scientific landscape. Theyre leading to unimaginable breakthroughs but leaving researchers racing to keep up. The post How Big Data Is Read more at Goodmenproject.com

Vedanta Biosciences Silvia Caballero, Ph.D., Named to TIME 100 NEXT List for Innovative Leaders[To top]

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Vedanta Biosciences Silvia Caballero, Ph.D., Named to TIME 100 NEXT List for Innovative Leaders
Read more at Businesswire.com

The morpho-genetic and ecological niche analyses reveal the existence of climatically restricted Cycas zeylanica complex in Sri Lanka[To top]

The morpho-genetic and ecological niche analyses reveal the existence of climatically restricted <i>Cycas zeylanica</i> complex in Sri Lanka Read more at Nature.com

Fast, sensitive and accurate integration of single-cell data with Harmony[To top]

Harmony, for the integration of single-cell transcriptomic data, identifies broad and fine-grained populations, scales to large datasets, and can integrate sequencing- and imaging-based data. Read more at Nature.com