A new treatment for glaucoma?

A Northwestern Medicine study in mice has identified new treatment targets for glaucoma, including preventing a severe pediatric form of glaucoma, as well as uncovering a possible new class of therapy for the most common form of glaucoma in adults. In people Read more at ScienceBlog.com

A mutational hotspot that determines highly repeatable evolution can be built and broken by silent genetic changes

Mutational hotspots can determine evolutionary outcomes and make evolution repeatable. Experiments in bacteria reveal that a powerfully deterministic genetic hotspot can be built and broken by a handful of silent mutations, highlighting an underappreciated ro Read more at Nature.com

Global Hybrid Rice Seeds Market Worth USD 5.43 Billion by 2027 | Escalating Global Consumption to Stoke Industry Growth, Says Fortune Business Insights

Companies covered in the global hybrid rice seeds market are Syngenta AG (Switzerland), Bayer AG (Germany), UPL Ltd. (India), Nath Bio-Genes Ltd. (India... Read more at Yahoo Entertainment

QIAGEN Launches Novel QIAreach QuantiFERON-TB Tuberculosis Test for High-Burden Regions

HILDEN, Germany & GERMANTOWN, Md.--(BUSINESS WIRE)---- $QGEN #qiareach--QIAGEN launches novel QIAreach QuantiFERON-TB tuberculosis test for high-burden regions Read more at Business Wire

Delta AY Sub-Variant, Which Requires 'Urgent Research', Found in These U.S. States

Former FDA commissioner Scott Gottlieb said scientists should study the Delta AY.4.2 subvariant due to it's U.K. spread
Read more at Newsweek

Effective sequence similarity detection with strobemers [METHOD]

k-mer-based methods are widely used in bioinformatics for various types of sequence comparisons. However, a single mutation will mutate k consecutive k-mers and make most k-mer-based applications for sequence comparison sensitive to variable mutation rates. M Read more at Cshlp.org

Snails associated with the coral-killing sponge Terpios hoshinota in Okinawa Island, Japan

Scientific Reports - <ArticleTitle Language="En" OutputMedium="All" xml:lang="en">Snails associated with the coral-killing sponge... Read more at Nature.com

Global Proteomics Market Report 2021-2026 - Proteomics to Enable Potent Antiviral Agents & Better Vaccines against COVID-19

DUBLIN, Oct. 18, 2021 /PRNewswire/ -- The "Proteomics - Global Market Trajectory & Analytics" report has been added to ResearchAndMarkets.com's offering. Global Proteomics Market to Reach $43.5 Billion by 2026 The proteomics market is anticipated to gain from Read more at PRNewswire

Jelastic PaaS is Now Available in China via CloudRaft Service Provider

Jelastic multi-cloud Platform-as-a-Service software, a product division of Virtuozzo, is now available in China through the partnership with CloudRaft, a Shanghai-based scientific computing service provider. We are glad to reach the Chinese cloud market with Read more at Jelastic.com

RgCop-A regularized copula based method for gene selection in single cell rna-seq data

Author Summary The existing approaches for gene selection which are based on high variation (highly variable genes) or significant high expression (highly expressed genes), failed to provide a stable and predictive feature/gene set. Since single cell data is Read more at Plos.org

Canntab Reaches Agreement with Innovative Bioinformatics Company, 36eight Technologies Inc.

TORONTO, Oct. 18, 2021 /PRNewswire/ - Canntab Therapeutics Limited (CSE: PILL.CN) (OTCQB: CTABF) (FRA: TBF1.F) (the "Company" or "Canntab"), the leading innovator in cannabinoid and terpene blends in hard pill form for therapeutic applications, is pleased to Read more at PRNewswire

Accurate inference of gene regulatory interactions from spatial gene expression with deep contrastive learning

Abstract Motivation Reverse engineering of gene regulatory networks (GRNs) has long been an attractive research topic in system biology. Computational prediction of gene regulatory interactions has remained a challenging problem due to the complexity of gen Read more at Oup.com

Multimodal medical image fusion using adaptive co-occurrence filter-based decomposition optimization model

Abstract Motivation Medical image fusion has developed into an important technology, which can effectively merge the significant information of multiple source images into one image. Fused images with abundant and complementary information are desirable, wh Read more at Oup.com

WGA-LP: a pipeline for Whole Genome Assembly of contaminated reads

Abstract Summary Whole Genome Assembly (WGA) of bacterial genomes with short reads is a quite common task as DNA sequencing has become cheaper with the advances of its technology. The process of assembling a genome has no absolute golden standard (Del Angel Read more at Oup.com

Leveraging auxiliary data from arbitrary distributions to boost GWAS discovery with Flexible cFDR

Author summary Genome-wide association studies (GWAS) detect regions of the human genome that are associated with various traits, including complex diseases, but the power to detect these genomic regions is currently limited by sample size. The conditional fa Read more at Plos.org

Machine learning to predict the source of campylobacteriosis using whole genome data

Author summary C. jejuni are the most common cause of food-borne bacterial gastroenteritis but the relative contribution of different sources is incompletely understood. We traced the origin of human C. jejuni infections using machine learning algorithms that Read more at Plos.org

Harnessing multimodal data integration to advance precision oncology

This Perspective proposes that data from multiple modalities, including molecular diagnostics, radiological and histological imaging and codified clinical data, should be integrated by multimodal machine learning models to advance the prognosis and treatment Read more at Nature.com

Mutations and variants of ONECUT1 in diabetes

Clinical and genetic phenotyping of consanguineous family cases of neonatal syndromic diabetes and type 2 diabetes, combined with in-depth functional studies in pluripotent stem cells, reveals a role for genetic variants of ONECUT1 in monogenic and multifacto Read more at Nature.com

Comments on USPTO Patent Eligibility Study Reveal Stark Contrast in Viewpoints of Some U.S. Patent Stakeholders

Friday, October 15, marked the final day of the public comment period for the U.S. Patent and Trademark Offices patent eligibility jurisprudence study. By the close of the comment period, 43 public comments were submitted from entities with very different vi Read more at IPWatchdog.com

Deficiency in cytosine DNA methylation leads to high chaperonin expression and tolerance to aminoglycosides in Vibrio cholerae

Author summary Bacteria are organisms with a remarkable ability to adapt to several stress conditions, including to the presence of antibiotics. The molecular mechanisms underlying such adaptation lead, very often, to phenomena like antimicrobial tolerance an Read more at Plos.org