Robust inference of bi-directional causal relationships in presence of correlated pleiotropy with GWAS summary data

Author summary Inferring causal relationships between two traits based on observational data is one of the most important as well as challenging problems in scientific research. The potential impact of such an application on and beyond genetics/genomics is si Read more at Plos.org

Podcast Episode: An AI Hammer in Search of a Nail

It often feels like machine learning experts are running around with a hammer, looking at everything as a potential nail - they have a system that does cool things and is fun to work on, and they go in search of things to use it for. But what if we flip that Read more at EFF

Taysha Gene Therapies, Inc. (TSHA) Q1 2022 Earnings Call Transcript

TSHA earnings call for the period ending March 31, 2022.
Read more at Motley Fool

Did the UK perform better than thought on Covid-19?

In the end the UK has had a very middling pandemic. That is the apparent message of a recent report by the World Health Organisation (WHO) that provides new estimates of the numbers of Covid-related d Read more at New Statesman

magenpy added to PyPI

Modeling and Analysis of Statistical Genetics data in python
Read more at Pypi.org

How Much Sleep Do You Need for Optimal Cognition, Well-Being? New Study Answers

A new research study, published in Nature Aging, provides an answer to how much sleep does our brain need to operate properly in the long term. The study suggests that seven hours of sleep per night was optimal, with more or less than that bringing fewer bene Read more at Gadgets360.com

Complete chloroplast genome of Coleanthus subtilis, a protected rare species

Coleanthus subtilis (Tratt.) Seidel (Poaceae) is a rare grass in the monotypic genus Coleanthus Seidl. It has been protected in many countries, such as the Czech Republic, North America and China, because of the extremely short life cycle, strict habitat and Read more at Phys.Org

What is the Role of Public Health in Addressing Health Equity in Genomics and Precision Medicine?

The following are excerpts from our recent paper in Genetics in Medicine. Although recent articles have included strong calls for a health equity agenda in genomics and precision medicine, these calls usually focus on underrepresentation of minority and ethni Read more at Cdc.gov

A year ago, she was a Bay Street lawyer. Now, Jules is a famous TikTok influencer

Since Julia Romano, sister of Blue Jay pitcher Jordan Romano, started posting videos on TikTok at the start of the pandemic, @julesthelawyer has amassed over 100,000 followers and 5.6 million likes. Read more at Toronto Star

High DDT resistance without apparent association to kdr and Glutathione-S-transferase (GST) gene mutations in Aedes aegypti population at hotel compounds in Zanzibar

Author summary Available information on mosquito resistance to insecticides is mainly restricted to residential and public areas, whereas commercial settings, such as hotels are overlooked. This may hide the real size of an insecticide resistance problem and Read more at Plos.org

Machine learning sequence prioritization for cell type-specific enhancer design

Recent discoveries of extreme cellular diversity in the brain warrant rapid development of technologies to access specific cell populations within heterogeneous tissue. Available approaches for engineering-targeted technologies for new neuron subtypes are low Read more at Elifesciences.org

The Greenrose Holding Company Reports First Quarter 2022 Results

Focus on Optimizing Inventory in Connecticut and Production Capacity in ArizonaImproving Positioning for Early-Stage Recreational Market...
Read more at Yahoo Entertainment

Are These Chemicals Part of a Depopulation Agenda?

In the After Skool video above, Shanna H. Swan, Ph.D., a leading environmental and reproductive epidemiologist and professor of environmental medicine and public health at the Icahn school of Medicine at Mount Sinai in New York City, examines the role of envi Read more at Mercola.com

Why does the whole shaadi discussion blend thinking and offer upwards instance strong responses?

Why does the whole shaadi discussion blend thinking and offer upwards instance strong responses? My personal h []
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Digging into diversity to understand diabetes

Researchers are searching large, diverse genetic databases to better understand the roots of diabetes in diverse populations. The post Digging into diversity to understand diabetes appeared first on Scope. Read more at Stanford.edu

Correlations from structure and phylogeny combine constructively in the inference of protein partners from sequences

Author summary In protein sequence data, the amino acid usages at different sites of a protein or of two interacting proteins can be correlated because of functional constraints. For instance, the need to maintain physico-chemical complementarity among two si Read more at Plos.org

CDF Announces Recipients of Inaugural Celiac Disease Research Prizes

New awards honor exceptional contributions to the field of celiac disease LOS ANGELES, May 17, 2022 /PRNewswire/ -- The Celiac Disease Foundation is pleased to announce the establishment of two international celiac disease research prizes. The Prize for Excel Read more at PRNewswire

How Science Fueled the White Supremacist Mass Murderer in Buffalo, NY

How Science Fueled the White Supremacist Mass Murderer in Buffalo, NYOver the weekend, a teenage male shooter perpetrated a horrific mass murder in a supermarket in Buffalo, New York, where 13 people were shot, and 10 died. All but two of the victims were bla Read more at Freerepublic.com

Epigenetic and transcriptional dysregulation in CD4+ T cells in patients with atopic dermatitis

Author summary Gene expression is regulated in stimulated CD4+ T cells in a disease-dependent manner in patients with atopic dermatitis (AD). AD-specific regions of chromatin accessibility and binding of the NFKB1 transcription factor are enriched for AD gene Read more at Plos.org

Pregnant and Have IBD? A GI Doc's Help Can Be Crucial

Women with IBD face several concerns related to their reproductive health decisions, from contraception to pregnancy to delivery. Research shows that IBD and certain drugs can impact fertility and pregnancy and pose risks for preterm birth and small gestation Read more at WebMD