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PROMALS3D

PROMALS3D

PROMALS (Profile Multiple Alignment with Local Structure) is a web-based tool for the construction of multiple sequence alignments (MSA). It searches both sequence and structure databases and uses that information together with user-defined constraints.

Topic

Structure prediction; Protein secondary structure; Proteins; Structure analysis; Sequence analysis

Details

  • Operation: Multiple sequence alignment; Protein secondary structure comparison; Protein secondary structure prediction
  • Input: FASTA
  • Output: Clustal; HTML
  • Software interface: Web user interface; command-line user interface
  • Language: Python
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: Not stated
  • Cost: Free
  • Version name: -
  • Maturity: Mature
  • Credit: The National Institutes of Health (GM094575 to NVG) and the Welch Foundation (I-1505 to NVG).
  • Contact: jpei _at_ chop.swmed.edu
  • Collection: -

Publications

Pei J, Grishin NV "PROMALS3D: multiple protein sequence alignment enhanced with evolutionary and three-dimensional structural information." Methods Mol Biol. 2014;1079:263-71. https://doi.org/10.1007/978-1-62703-646-7_17
PMID: 24170408
PMCID: PMC4506754


Pei J, Kim BH, Grishin NV "PROMALS3D: a tool for multiple protein sequence and structure alignments." Nucleic Acids Res. 2008 Apr;36(7):2295-300. https://doi.org/10.1093/nar/gkn072
PMID: 18287115
PMCID: PMC2367709


Pei J, Tang M, Grishin NV "PROMALS3D web server for accurate multiple protein sequence and structure alignments." Nucleic Acids Res. 2008 Jul 1;36(Web Server issue):W30-4. https://doi.org/10.1093/nar/gkn322
PMID: 18503087
PMCID: PMC2447800


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