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APTANI

APTANI

APTANI is a tool for the identification of aptamers (synthetic nucleic acid molecules that can bind biological targets) from HT-SELEX data and secondary structure information.

Topic

Nucleic acid structure analysis; Nucleic acid sites, features and motifs

Details

  • Operation: Nucleic acid feature detection; RNA structure prediction
  • Software interface: Command-line user interface
  • Language: Python
  • Operating system: Linux
  • License: Not stated
  • Cost: Free
  • Version name: 1.4
  • Credit: The Italian Ministry of Education, University and Research and EPIGEN - Italian Flagship Project Epigenomics, AIRC Special Program Molecular Clinical Oncology 5x1000, the JDRF foundation
  • Contact: silvio.bicciato _at_ unimore.it
  • Collection: -

Publications

Caroli J, Taccioli C, De La Fuente A, Serafini P, Bicciato S "APTANI: a computational tool to select aptamers through sequence-structure motif analysis of HT-SELEX data." Bioinformatics. 2016 Jan 15;32(2):161-4. 2015 Sep 22. https://doi.org/10.1093/bioinformatics/btv545
PMID: 26395772


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