MaxQuant is a tool for the analysis of large mass-spectrometric data sets. The MaxQuant algorithm can manage large high-resolution data sets, uses many labeling procedures, and label-free quantification. MaxQuant has a viewer module to visualize 3-D graphical models. See also Perseus framework for statistical analysis of MaxQuant output.
Proteomics; Proteomics experiment; Statistics and probability
Cox J, Mann M "MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification." Nat Biotechnol, 2008 https://doi.org/10.1038/nbt.1511
PMID: 19029910
PMCID: None
Tyanova S, Temu T, Carlson A, Sinitcyn P, Mann M, Cox J "Visualization of LC-MS/MS proteomics data in MaxQuant." Proteomics, 2015 https://doi.org/10.1002/pmic.201400449
PMID: 25644178
PMCID: PMC5024039
Cox J, Michalski A, Mann M "Software lock mass by two-dimensional minimization of peptide mass errors." J Am Soc Mass Spectrom, 2011 https://doi.org/10.1007/s13361-011-0142-8
PMID: 21953191
PMCID: PMC3231580
Tyanova S, Temu T, Cox J "The MaxQuant computational platform for mass spectrometry-based shotgun proteomics." Nat Protoc, 2016 https://doi.org/10.1038/nprot.2016.136
PMID: 27809316
PMCID: None
Schaab C, Geiger T, Stoehr G, Cox J, Mann M "Analysis of high accuracy, quantitative proteomics data in the MaxQB database." Mol Cell Proteomics, 2012 https://doi.org/10.1074/mcp.M111.014068
PMID: 22301388
PMCID: PMC3316731
Cox J, Hein MY, Luber CA, Paron I, Nagaraj N, Mann M "Accurate proteome-wide label-free quantification by delayed normalization and maximal peptide ratio extraction, termed MaxLFQ." Mol Cell Proteomics, 2014 https://doi.org/10.1074/mcp.M113.031591
PMID: 24942700
PMCID: PMC4159666
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