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Multi-Q

Multi-Q

Multi-Q is a tool to analyze multiplexed iTRAQ data. The Multi-Q has functions for calculation of peptide ratios, detection and processing iTRAQ’s signature peaks, background subtraction, isotope correction, normalization, and data filtering using empirical or statistical models. Multi-Q works with various input formats from different search engines and mass spectrometers.

Topic

Proteomics; Proteomics experiment

Details

  • Operation: Formatting; Peak detection; iTRAQ; Validation of peptide-spectrum matches; Protein quantification; Labeled quantification
  • Input: WIFF, mzXML, orotXML,pepXML
  • Output: mzXML, CSV, XML
  • Software interface: Graphical user interface
  • Language: Perl
  • Operating system: Microsoft Windows
  • License: Other
  • Cost: Free
  • Version name: -
  • Credit: Academia Sinica
  • Contact: bioinfo _at_ iis.sinica.edu.tw
  • Collection: -

Publications

Lin WT, Hung WN, Yian YH, Wu KP, Han CL, Chen YR, Chen YJ, Sung TY, Hsu WL "Multi-Q: a fully automated tool for multiplexed protein quantitation." J. Proteome Res. 2006; 5(9):2328-38 https://doi.org/10.1021/pr060132c
PMID: 16944945


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