BCseq (bias-corrected sequencing analysis) is a tool to quantify and correct bias in single-cell RNA-seq data sets. The BCseq algorithm detects dropouts by measurement of outputs from similar cells and assigns a quality score for each gene.
Gene expression; RNA-seq; Sequencing; Transcriptomics
Chen L, Zheng S "BCseq: accurate single cell RNA-seq quantification with bias correction." Nucleic Acids Res. 2018 Aug 21;46(14):e82. https://doi.org/10.1093/nar/gky308
PMID: 29718338
PMCID: PMC6101504
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