BEELINE (Benchmarking gEnE reguLatory network Inference from siNgle-cEll) is a tool for benchmarking algorithms inferring gene regulatory networks (GRNs). The BEELINE algorithm simulates single-cell expression data and uses artificial networks having predictable cell trajectories and Boolean models to evaluate the accuracy of inferences.
RNA-seq; Transcriptomics; Molecular interactions, pathways and networks; Gene expression
Aditya Pratapa, View ORCID ProfileAmogh P. Jalihal, View ORCID ProfileJeffrey N. Law, View ORCID ProfileAditya Bharadwaj, View ORCID ProfileT. M. Murali "Benchmarking algorithms for gene regulatory network inference from single-cell transcriptomic data" biorxiv.org https://doi.org/10.1101/642926
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