BPSC (Beta-Poisson model for Single-Cell RNA-seq data analyses) is an R tool for the examination of single-cell RNA-seq data. The BPSC algorithm uses a beta-Poisson mixture model to estimate the bimodality of expression distribution.
Genetic variation; RNA-seq
Vu TN, Wills QF, Kalari KR, Niu N, Wang L, Rantalainen M, Pawitan Y "Beta-Poisson model for single-cell RNA-seq data analyses." Bioinformatics. 2016 Jul 15;32(14):2128-35. Epub 2016 Apr 19. https://doi.org/10.1093/bioinformatics/btw202
PMID: 27153638
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