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BTR

BTR

BTR is an R tool for analysis of differential gene expression in single-cell RNA-seq data. The BTR algorithm learns models and expression data using a new Boolean state space scoring function.

Topic

RNA-seq; Transcriptomics; Gene expression

Details

  • Operation: RNA-Seq analysis
  • Software interface: Command-line user interface; Library
  • Language: R
  • Operating system: Microsoft Windows, Mac OS X, Linux
  • License: GNU General Public License v3
  • Cost: Free
  • Version name: 1.2.4
  • Maturity: Stable
  • Credit: Bloodwise, Cancer Research UK, the Biotechnology and Biological Sciences Research Council, NIHR Cambridge Biomedical Research Centre Award, Microsoft Research and core support grants by the Wellcome Trust to the Cambridge Institute for Medical Research and Wellcome Trust - MRC Cambridge Stem Cell Institute.
  • Contact: Chee Yee Lim cyl49 _at_ cam.ac.uk
  • Collection: -

Publications

Lim CY, Wang H, Woodhouse S, Piterman N, Wernisch L, Fisher J, Gottgens B "BTR: training asynchronous Boolean models using single-cell expression data." BMC Bioinformatics. 2016 Sep 6;17(1):355. https://doi.org/10.1186/s12859-016-1235-y
PMID: 27600248
PMCID: PMC5012073


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