BUSseq (Batch Effects Correction with Unknown Subtypes for scRNA seq) is an R tool to correct batch effects in single-cell RNA-seq data. The BUSseq algorithm can also cluster cell types, correct for overdispersion, cell-specific sequencing depth, and dropout events.
RNA-seq; Transcriptomics
Fangda Song, Ga Ming Chan, Yingying Wei "Flexible Experimental Designs for Valid Single-cell RNA-sequencing Experiments Allowing Batch Effects Correction" biorxiv.org https://doi.org/10.1101/533372
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