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Bisque (ucla)

Bisque (ucla)

Bisque is an R tool to estimate cell composition from single-cell RNA-seq data. The Bisque algorithm uses a regression approach to compute reference expression profiles and, consequently, to learn gene-specific bulk expression transformations for decomposition.

Topic

RNA-seq; Transcriptomics

Details

  • Operation: RNA-Seq analysis
  • Software interface: Command-line user interface; Library
  • Language: R
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: GNU General Public License v3
  • Cost: Free
  • Version name: 1.0
  • Maturity: Emerging
  • Credit: NIA, the National Science Foundation (NSF), The Howard Hughes Medical Institute (HHMI), AHA.
  • Contact: Eran Halperin ehalperin _at_ cs.ucla.edu
  • Collection: -

Publications

Jew Brandon, Alvarez Marcus, Rahmani Elior, Miao Zong, Ko Arthur, Sul Jae Hoon, Pietiläinen Kirsi H., Pajukanta Päivi, Halperin Eran "Accurate estimation of cell composition in bulk expression through robust integration of single-cell information" bioRxiv https://doi.org/10.1101/669911


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