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CaSTLe

CaSTLe

A tool for the classification of cells in single-cell RNA-seq data. The CaSTLe algorithm applies information transferred from past experiments with similar cell types and the XGBoost classification model to label cells.

Topic

Transcriptomics; RNA-seq

Details

  • Operation: RNA-Seq analysis
  • Software interface: Command-line user interface; Library
  • Language: R
  • Operating system: Microsoft Windows, Mac OS X, Linux
  • License: Not stated
  • Cost: Free
  • Version name: -
  • Credit: Israel Science Foundation, Broad-Israel Science Foundation, the National Institutes of Health (NIH).
  • Contact: Yuval Lieberman yuvalli _at_ post.bgu.ac.il | talshay _at_ bgu.ac.il Tal Shay
  • Collection: -

Publications

Lieberman Y, Rokach L, Shay T "CaSTLe - Classification of single cells by transfer learning: Harnessing the power of publicly available single cell RNA sequencing experiments to annotate new experiments." PLoS One. 2018 Oct 10;13(10):e0205499. eCollection 2018. https://doi.org/10.1371/journal.pone.0205499
PMID: 30304022
PMCID: PMC6179251


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