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CellRouter

CellRouter

CellRouter is a tool for the identification of cell-state transition trajectories in single-cell RNA-seq data. The CellRouter algorithm uses flow networks to identify subpopulations.

Topic

Cell biology; Transcriptomics; RNA-seq

Details

  • Operation: RNA-Seq analysis
  • Software interface: Command-line user interface; Library
  • Language: R
  • Operating system: Microsoft Windows, Mac OS X, Linux
  • License: Not stated
  • Cost: Free
  • Version name: -
  • Maturity: Stable
  • Credit: US National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Allergy and Infectious Diseases, the National Heart, Lung, Blood Institute Progenitor Cell Biology Consortium, the Progenitor Cell Translation Consortium, the Doris Duke Medical Foundation, the St. Baldrick's Foundation, and Pedals for Pediatrics, he Wenner-Gren Foundation, he Howard Hughes Medical Institute.
  • Contact: James J. Collins jimjc _at_ mit.edu
  • Collection: -

Publications

Lummertz da Rocha E, Rowe RG, Lundin V, Malleshaiah M, Jha DK, Rambo CR, Li H, North TE, Collins JJ, Daley GQ "Reconstruction of complex single-cell trajectories using CellRouter." Nat Commun. 2018 Mar 1;9(1):892. https://doi.org/10.1038/s41467-018-03214-y
PMID: 29497036
PMCID: PMC5832860


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