D3E is a tool for the identification of differentially expressed genes in single-cell RNA-seq (scRNA-seq) data. The D3E algorithm has a function to fit the parameters of a Poisson-Beta distribution. A web-based version is available for the analysis of small datasets (see links).
RNA-seq; Gene expression
Delmans M, Hemberg M "Discrete distributional differential expression (D3E)--a tool for gene expression analysis of single-cell RNA-seq data" BMC Bioinformatics. 2016 Feb 29;17:110. https://doi.org/10.1186/s12859-016-0944-6
PMID: 26927822
PMCID: PMC4772470
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