DECENT is an R tool for differential expression analysis of single-cell RNA-seq data. The DECENT algorithm requires UMIs and it has a hierarchical approach in modeling the observed and unobserved counts to detect dropouts.
Gene expression; RNA-seq; Sequencing; Transcriptomics
Ye C, Speed TP, Salim A "DECENT: Differential Expression with Capture Efficiency adjustmeNT for single-cell RNA-seq data." Bioinformatics. 2019 Jun 14. pii: 5514046. https://doi.org/10.1093/bioinformatics/btz453
PMID: 31197307
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