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DPT

DPT

DPT (Diffusion pseudotime) is a tool to estimate the temporal order of differentiating cell in single-cell RNA-seq (scRNA-seq) data. The DPT algorithm using diffusion-like random walks to estimate transitions between cells.

Topic

RNA-seq

Details

  • Operation: RNA-Seq analysis
  • Software interface: Command-line user interface; Library
  • Language: R, Python
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: GPL-3
  • Cost: Free
  • Version name: 3.0.1
  • Maturity: Mature
  • Credit: Medical Research Council, United Kingdom.
  • Contact: Philipp Angerer philipp.angerer at helmholtz-muenchen.de
  • Collection: -

Publications

Haghverdi L, Büttner M, Wolf FA, Buettner F, Theis FJ "Diffusion pseudotime robustly reconstructs lineage branching" Nat Methods. 2016 Oct;13(10):845-8. https://doi.org/10.1038/nmeth.3971
PMID: 27571553


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