GGEA (Gene Graph Enrichment Analysis) is a tool for the detection of enriched gene sets in RNA-seq datasets. The GGEA algorithm uses prior knowlede obtained from gene regulatory networks.
Systems biology; Gene expression; RNA-Seq; Molecular interactions, pathways and networks
Geistlinger L, Csaba G, Küffner R, Mulder N, Zimmer R "From sets to graphs: towards a realistic enrichment analysis of transcriptomic systems." Bioinformatics 2011; 27(13):i366-73 https://doi.org/10.1093/bioinformatics/btr228
PMID: 21685094
PMCID: PMC3117393
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