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GMM-demux

GMM-demux

GMM-demux is a tool to remove Multi-Sample-Multiplets in a cell hashing dataset and to estimate the fraction of Same-Sample-Multiplets and singlets in barcoded single-cell RNA-seq (scRNA-seq) data.

Topic

RNA-seq

Details

  • Operation: RNA-Seq analysis
  • Software interface: Command-line user interface
  • Language: Python
  • Operating system: Linux; Mac OS X
  • License: The MIT licence
  • Cost: Free
  • Version name: -
  • Credit: National Institute of Health (NIH), Children's Hospital of Pittsburgh.
  • Contact: Wei Chen wec47 _at_ pitt.edu | Kong Chen koc5 _at_ pitt.edu
  • Collection: -

Publications

Hongyi Xin, Qi Yan, Yale Jiang, Qiuyu Lian, Jiadi Luo, Carla Erb, Richard Duerr, Kong Chen, Wei Chen "Sample demultiplexing, multiplet detection, experiment planning and novel cell type verification in single cell sequencing" bioRxiv https://doi.org/10.1101/828483


Download and documentation








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