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GRNVBEM

GRNVBEM

GRNVBEM is a tool to infer gene regulatory network (GRN) from time-series or pseudo-time series in single-cell RNA-seq (scRNA-seq) data. The GRNVBEM algorithm uses a first-order autoregressive moving average model and a variational Bayesian Expectation-Maximization.

Topic

RNA-Seq; Gene expression

Details

Publications

Sanchez-Castillo M, Blanco D, Tienda-Luna IM, Carrion MC, Huang Y "A Bayesian Framework for the Inference of Gene Regulatory Networks From Time and Pseudo-Time Series Data " Bioinformatics. 2018 Mar 15;34(6):964-970. https://doi.org/10.1093/bioinformatics/btx605
PMID: 29028984


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