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IUTA

IUTA

IUTA is a tool for the detection of isoform usage in RNA-seq data sets generated by Illumina paired-end sequencing. The IUTA algorithm uses two probability distributions under the Aitchison geometry to test equal mean values.

Topic

RNA-seq; Transcriptomics; Genetics

Details

  • Operation: Gene expression profiling
  • Software interface: Library
  • Language: R
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: GNU Lesser General Public License v2
  • Cost: Free
  • Version name: 1.0
  • Credit: Intramural Research Program of the NIH, National Institute of Environmental Health Sciences.
  • Contact: David M. Umbach, Ph.D. umbach _at_ niehs.nih.gov | Leping Li, Ph.D. li3 _at_ niehs.nih.gov
  • Collection: -

Publications

Niu L, Huang W, Umbach DM, Li L "IUTA: a tool for effectively detecting differential isoform usage from RNA-Seq data." BMC Genomics 2014 https://doi.org/10.1186/1471-2164-15-862
PMID: 25283306
PMCID: PMC4195885


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