MAGIC (Markov Affinity-based Graph Imputation of Cells) is a tool for denoising high-dimensional single-cell RNA-seq data. The MAGIC algorithm works by information sharing over alike cells to denoise cell counts and to detect dropouts.
Transcriptomics; RNA-seq
van Dijk D, Sharma R, Nainys J, Yim K, Kathail P, Carr AJ, Burdziak C, Moon KR, Chaffer CL, Pattabiraman D, Bierie B, Mazutis L, Wolf G, Krishnaswamy S, Pe'er D "Recovering Gene Interactions from Single-Cell Data Using Data Diffusion." Cell. 2018 Jul 26;174(3):716-729.e27. Jun 28. https://doi.org/10.1016/j.cell.2018.05.061
PMID: 29961576
PMCID: PMC6771278
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