MUSIC is an R tool to analyze single-cell data from a combination of Perturb-Seq, CRISP-seq, CROP-seq, and single-cell RNA-seq. The MUSIC algorithm analysis step consists of preprocessing, model construction, and perturbation impact prioritizing.
Gene expression; Transcriptomics; RNA-seq
Duan B, Zhou C, Zhu C, Yu Y, Li G, Zhang S, Zhang C, Ye X, Ma H, Qu S, Zhang Z, Wang P, Sun S, Liu Q "Model-based understanding of single-cell CRISPR screening." Nat Commun. 2019 May 20;10(1):2233. https://doi.org/10.1038/s41467-019-10216-x
PMID: 31110232
PMCID: PMC6527552
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