A tool to assemble and quantify transcripts in Ion Torrent RNA-seq data sets. The MaLTA uses the IsoEM algorithm for the estimation of expression levels. It also uses a maximum likelihood method in both assembly and quantification steps.
A tool to assemble and quantify transcripts in Ion Torrent RNA-seq data sets. The MaLTA uses the IsoEM algorithm for the estimation of expression levels. It also uses a maximum likelihood method in both assembly and quantification steps.
Credit:
USDA National Institute of Food and Agriculture, Life Technology Grants "Novel transcript reconstruction from Ion Torrent sequencing" and "Viral Metagenome Reconstruction Software for Ion Torrent PGM Sequencer," National Science Foundation (NSF), National Institutes of Health (NIH), Institute for Quantitative & Computational Biosciences, UCLA, Second Century Initiative Bioinformatics University Doctoral Fellowship, Georgia State University, Molecular Basis of Disease Fellowship, Georgia State University.
Mangul S, Caciula A, Al Seesi S, Brinza D, Mndoiu I, Zelikovsky A "Transcriptome assembly and quantification from Ion Torrent RNA-Seq data." BMC Genomics. 2014;15 Suppl 5:S7. 14. https://doi.org/10.1186/1471-2164-15-S5-S7
PMID: 25082147
PMCID: PMC4120146