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NPEBseq

NPEBseq

NPEBseq is an R tool for differential gene expression analysis of RNA-seq data. The NPEBseq algorithm uses an empirical Bayesian model with the prior distribution estimation from the data itself. NPEBseq can estimate differential expression on both gene and exon levels.

Topic

RNA-seq; Transcriptomics; Gene expression

Details

  • Operation: Differential gene expression analysis
  • Software interface: Command-line user interface
  • Language: R
  • Operating system: Microsoft Windows, Mac OS X, Linux
  • License: GNU General Public License v>=2
  • Cost: Free
  • Version name: -
  • Credit: Commonwealth Universal Research Enhancement (CURE) Research Program, Department of Health, Pennsylvania, Philadelphia Healthcare Trust, National Library Of Medicine of the National Institutes of Health.
  • Contact: Yingtao Bi ybi _at_ wistar.org | Ramana V Davuluri rdavuluri _at_ wistar.org
  • Collection: -

Publications

Bi Y, Davuluri RV "NPEBseq: nonparametric empirical bayesian-based procedure for differential expression analysis of RNA-seq data." BMC Bioinformatics. 2013 Aug 27;14:262. https://doi.org/10.1186/1471-2105-14-262
PMID: 23981227
PMCID: PMC3765716


Download and documentation

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