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Outrigger

Outrigger

Outrigger is a tool for the creation of de novo alternative splicing annotation for RNA-seq data. The Outrigger uses junction reads, a graph database, and quantifies spliced-in (Psi) events.

Topic

Sequencing; RNA-seq; Transcriptomics

Details

  • Operation: Differential gene expression analysis; Splicing model analysis
  • Software interface: Command-line user interface
  • Language: Python
  • Operating system: Linux; Microsoft Windows; Mac OS X
  • License: BSD 3-Clause "New" or "Revised" License
  • Cost: Free
  • Version name: -
  • Maturity: Mature
  • Credit: The National Institutes of Health (NIH), the California Institute of Regenerative Medicine, the Brain Research Foundation, Alfred P. Sloan, National Defense Science, NumFOCUS John Hunter Technology.
  • Contact: Gene W. Yeo geneyeo _at_ ucsd.edu
  • Collection: Expedition

Publications

Song Y, Botvinnik OB, Lovci MT, Kakaradov B, Liu P, Xu JL, Yeo GW "Single-Cell Alternative Splicing Analysis with Expedition Reveals Splicing Dynamics during Neuron Differentiation." Mol Cell. 2017 Jul 6;67(1):148-161.e5. 2017 Jun 29. https://doi.org/10.1016/j.molcel.2017.06.003
PMID: 28673540
PMCID: PMC5540791


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