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PINTA

PINTA

PINTA is a web-based tool to prioritize candidate genes based on their genome-wide protein-protein interaction network neighborhood and differential gene expression. PINTA works for human, mouse, rat, worm, and yeast data.

Topic

Protein interactions; Molecular interactions, pathways and networks; Model organisms; Model organisms; Human biology

Details

  • Operation: Pathway or network visualisation; Differential gene expression analysis; Gene expression profiling; Protein-protein interaction prediction
  • Software interface: Web user interface
  • Language: PHP;MATLAB
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: Not stated
  • Cost: Free
  • Version name: -
  • Credit: Research Council KUL, Flemish Government, Belgian Federal Science Policy Office, ERNSI: European Research Network on System Identification, PIDDAC Program funds and NEUROCLINOMICS.
  • Contact: Prof. Yves Moreau yves.moreau _at_ esat.kuleuven.be
  • Collection: -

Publications

Nitsch D, Gonçalves JP, Ojeda F, de Moor B, Moreau Y "PINTA: a web server for network-based gene prioritization from expression data." Nucleic Acids Res. 2011 Jul;39(Web Server issue):W334-8. doi: 10.1093/nar/gkr289. Epub 2011 May 20. https://doi.org/10.1093/nar/gkr289x
PMID: 21602267
PMCID: PMC3125740


Nitsch D, Tranchevent LC, Thienpont B, Thorrez L, Van Esch H, Devriendt K, Moreau Y "Network analysis of differential expression for the identification of disease-causing genes." PLoS One. 2009;4(5):e5526. doi: 10.1371/journal.pone.0005526. Epub 2009 May 13. https://doi.org/10.1371/journal.pone.0005526
PMID: 19436755
PMCID: PMC2677677


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