PINTA is a web-based tool to prioritize candidate genes based on their genome-wide protein-protein interaction network neighborhood and differential gene expression. PINTA works for human, mouse, rat, worm, and yeast data.
Protein interactions; Molecular interactions, pathways and networks; Model organisms; Model organisms; Human biology
Nitsch D, Gonçalves JP, Ojeda F, de Moor B, Moreau Y "PINTA: a web server for network-based gene prioritization from expression data." Nucleic Acids Res. 2011 Jul;39(Web Server issue):W334-8. doi: 10.1093/nar/gkr289. Epub 2011 May 20. https://doi.org/10.1093/nar/gkr289x
PMID: 21602267
PMCID: PMC3125740
Nitsch D, Tranchevent LC, Thienpont B, Thorrez L, Van Esch H, Devriendt K, Moreau Y "Network analysis of differential expression for the identification of disease-causing genes." PLoS One. 2009;4(5):e5526. doi: 10.1371/journal.pone.0005526. Epub 2009 May 13. https://doi.org/10.1371/journal.pone.0005526
PMID: 19436755
PMCID: PMC2677677
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