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Palantir

Palantir

A tool for computation of cellular differentiation trajectories in single-cell RNA-seq and Mass cytometry data. The Palantir algorithm models differentiation as a stochastic process to estimate cell fates.

Topic

RNA-seq; Gene expression

Details

  • Operation: RNA-Seq analysis
  • Software interface: Command-line user inerface
  • Language: Python
  • Operating system: Microsoft Windows, Mac OS X, Linux
  • License: GNU GPL v2
  • Cost: Free
  • Version name: -
  • Credit: The National Institutes of Health NIH, the Gerry Center for Metastasis and Tumor Ecosystems.
  • Contact: Dana Pe’er peerd _at_ mskcc.org
  • Collection: -

Publications

Setty M, Kiseliovas V, Levine J, Gayoso A, Mazutis L, Pe'er D "Characterization of cell fate probabilities in single-cell data with Palantir." Nat Biotechnol. 2019 Apr;37(4):451-460. Mar 21. https://doi.org/10.1038/s41587-019-0068-4
PMID: 30899105


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