RDiff is a tool for the detection of differential RNA processing in RNA-seq data. The RDiff algorithm can identify and quantify novel and known isoforms. The RDiff provides a parametric test for annotated genomes and a non-parametric version for genomes where the annotation is incomplete.
RNA splicing; RNA-Seq; Transcriptomics
Drewe P, Stegle O, Hartmann L, Kahles A, Bohnert R, Wachter A, Borgwardt K, Rätsch G "Accurate detection of differential RNA processing." Nucleic Acids Res. 2013; 41(10):5189-98 https://doi.org/10.1093/nar/gkt211
PMID: 23585274
PMCID: PMC3664801
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