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SIGN

SIGN

SIGN (Similarity Identification in Gene expressioN) is a tool for the analysis of expression patterns and pathways in RNA-seq data. The SIGN algorithm identifies similarities between biological sample sets.

Topic

RNA-Seq; Molecular interactions, pathways and networks; Genetics

Details

  • Operation: Pathway or network analysis; Gene-set enrichment analysis
  • Software interface: Command-line user interface; Library
  • Language: R
  • Operating system: Microsoft Windows, Mac OS X, Linux
  • License: GNU General Public License v>=3
  • Cost: Free
  • Version name: 0.1.0
  • Credit: Cancer Research Society and the Ontario Institute for Cancer Research, Government of Ontario, Connaught International Scholarships, Genome Canada and the Ontario Research Funds, Cancer Research Society, Gattuso-Slaight Personalized Cancer Medicine Fund at Princess Margaret Cancer Centre, the Natural Sciences and Engineering Research Council, and the Canadian Institutes of Health Research.
  • Contact: Benjamin Haibe-Kains benjamin.haibe.kains _at_ utoronto.ca
  • Collection: -

Publications

Madani Tonekaboni SA, Manem VSK, El-Hachem N, Haibe-Kains B "SIGN: similarity identification in gene expression." Bioinformatics. 2019 Nov 1;35(22):4830-4833. https://doi.org/10.1093/bioinformatics/btz485
PMID: 31198954
PMCID: PMC6853666


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