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SINCERA

SINCERA

SINCERA is a pipeline tool for profiling, analysis, and visualization of single-cell RNA-seq (scRNA-seq) data. The SINCERA algorithm has functions for the identification of cell type specific gene signatures, and the computation of driving forces of cell types.

Topic

RNA-seq

Details

  • Operation: RNA-Seq analysis
  • Software interface: Command-line user interface
  • Language: R
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: GNU General Public License v3
  • Cost: Free
  • Version name: 0.99.0
  • Maturity: Stable
  • Credit: The National Heart, Lung, and Blood Institute of National Institutes of Health.
  • Contact: Yan Xu yan.xu _at_ cchmc.org
  • Collection: -

Publications

Guo M, Wang H, Potter SS, Whitsett JA, Xu Y "SINCERA: A Pipeline for Single-Cell RNA-Seq Profiling Analysis." PLoS Comput Biol. 2015 Nov 24;11(11):e1004575. https://doi.org/10.1371/journal.pcbi.1004575
PMID: 26600239
PMCID: PMC4658017


Guo M, Xu Y "Single-Cell Transcriptome Analysis Using SINCERA Pipeline." Methods Mol Biol. 2018;1751:209-222. https://doi.org/10.1007/978-1-4939-7710-9_15
PMID: 29508300
PMCID: PMC6699487


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