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SLICE

SLICE

SLICE is a tool to estimate cellular differentiation states in single-cell RNA-seq (scRNA-seq) data. The SLICE algorithm also predicts differentiation lineages by computing cell trajectory entropies.

Topic

Gene expression; RNA-seq

Details

  • Operation: RNA-Seq analysis; Prediction and recognition
  • Software interface: Command-line user interface
  • Language: R
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: GPL-3
  • Cost: Free
  • Version name: a12242016
  • Credit: National Heart, Lung and Blood Institute of National Institutes of Health.
  • Contact: Yan Xu yan.xu _at_ cchmc.org
  • Collection: -

Publications

Guo M, Bao EL, Wagner M, Whitsett JA, Xu Y "SLICE: determining cell differentiation and lineage based on single cell entropy." Nucleic Acids Res. 2017 Apr 20;45(7):e54. https://doi.org/10.1093/nar/gkw1278
PMID: 27998929
PMCID: PMC5397210


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