SigEMD is an R tool to identify differential expression in single-cell RNA-seq data. The SigEMD algorithm uses imputation, logistic regression, gene interaction network information, and a nonparametric method based on the Earth Mover's Distance for the identification.
RNA-seq; Gene expression
Wang T, Nabavi S "SigEMD: A powerful method for differential gene expression analysis in single-cell RNA sequencing data." Methods. 2018 Aug 1;145:25-32. 24. https://doi.org/10.1016/j.ymeth.2018.04.017
PMID: 29702224
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