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Solas

Solas

Solas is a tool to predict and quantify expressed isoforms within observed coding regions in RNA-seq data. The Solas algorithm has three separate functions: 1. detection of alternative splicing events differentiating two conditions, 2. detection of genes and exons being part of an alternative splicing event, 3. quantification of the relative proportion of isoforms.

Topic

Gene expression; Statistics and probability; Data mining; RNA-Seq

Details

  • Operation: Nucleic acid feature detection; Splicing model analysis; RNA-Seq quantification; RNA-Seq analysis
  • Software interface: Command-line user interface; Library
  • Language: R
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: Not stated
  • Cost: Free
  • Version name: 0.2.1
  • Credit: Max Planck Society and the European Union. Funding for open access charge: Max-Planck Society.
  • Contact: Hugues Richard richard _at_ molgen.mpg.de
  • Collection: -

Publications

Richard H, Schulz MH, Sultan M, Nürnberger A, Schrinner S, Balzereit D, Dagand E, Rasche A, Lehrach H, Vingron M, Haas SA, Yaspo ML "Prediction of alternative isoforms from exon expression levels in RNA-Seq experiments." Nucleic Acids Res. 2010; 38(10):e112 https://doi.org/10.1093/nar/gkq041
PMID: 20150413
PMCID: PMC2879520


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