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anota2seq

anota2seq

anota2seq is a tool for the analysis of translational efficiency and differential expression analysis for polysome-profiling and ribosome-profiling studies that are quantified by RNA-seq or DNA-microarray.

Topic

Gene expression; Gene regulation; GWAS study; Microarray experiment; RNA-seq; Sequencing

Details

  • Operation: Differential gene expression analysis; Standardisation and normalisation; Regression analysis
  • Software interface: Command-line user interface; Library
  • Language: R
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: GPL-3.0
  • Cost: Free
  • Version name: 1.8.0
  • Maturity: Stable
  • Credit: Swedish Research Council; Swedish Cancer Society; Cancer Society in Stockholm; Wallenberg Academy Fellows Program, STRATCAN, Canadian Institutes for Health Research, National Institutes of Health, the Fonds de Recherche du Québec – Santé (FRQ-S), Joint Canada-Israel Health Research Program (JCIHRP), Department of Health and Human Services acting through the Victorian Cancer Agency, National Health and Medical Research Council (NHMRC), VetenskapsrÃ¥det.
  • Contact: Christian Oertlin christian.oertlin _at_ ki.se, Julie Lorent julie.lorent _at_ ki.se
  • Collection: Bioconductor

Publications

Oertlin C, Lorent J, Murie C, Furic L, Topisirovic I, Larsson O "Generally Applicable Transcriptome-Wide Analysis of Translation Using anota2seq" Nucleic Acids Res. 2019;47(12):e70. https://doi.org/10.1093/nar/gkz223
PMID: 30926999
PMCID: PMC6614820


Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J1, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M "Orchestrating high-throughput genomic analysis with Bioconductor." Nat Methods. 2015 Feb;12(2):115-21. https://doi.org/10.1038/nmeth.3252
PMID: 25633503
PMCID: PMC4509590


Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JY, Zhang J. "Bioconductor: open software development for computational biology and bioinformatics." Genome Biol. 2004;5(10):R80. Epub 2004 Sep 15. https://doi.org/10.1186/gb-2004-5-10-r80
PMID: 15461798
PMCID: PMC545600


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